Recherche
Cancer du sein, Microenvironnement et Immunociblage : E. Liaudet-Coopman

Desroys du Roure P, Lajoie L, Mallavialle A, Alcaraz L, Mansouri H, Fenou L, Garambois V, Rubio L, David T, Coenon L, Boissière-Michot F, Chateau M-C, Ngo G, Jarlier M, Villalba M, Martineau P, Laurent-Matha V, Roger P, Guiu S, Chardès T, Gros L, Liaudet-Coopman E A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer. J Immunother Cancer. 2024;12(1):e007135. doi:10.1136/jitc-2023-007135

Shoji K, Bayet E, Leverrier-Penna S, Le Devedec D, Mallavialle A, Marionneau-Lambot S, Rambow F, Perret R, Joussaume A, Viel R, Fautrel A, Khammari A, Constantin B, Tartare-Deckert S, Penna A The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential. EMBO Rep. 2023-02-06. doi:10.15252/embr.202255069

Huober J, Weder P, Ribi K, Thürlimann B, Li Q, Vanlemmens L, Guiu S, Brain E, Grenier J, Dalenc F, Levy C, Savoye A-M, Müller A, Membrez-Antonioli V, Gérard M-A, Lemonnier J, Hawle H, Dietrich D, Boven E, Bonnefoi H Pertuzumab Plus Trastuzumab With or Without Chemotherapy Followed by Emtansine in ERBB2-Positive Metastatic Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2023-08-10. doi:10.1001/jamaoncol.2023.2909

François-Martin H, Pistilli B, Levy C, Frenel J-S, Guiu S, Mouret-Reynier M-A, Mailliez A, Eymard J-C, Petit T, Ung M, Desmoulins I, Augereau P, Bachelot T, Uwer L, Debled M, Ferrero J-M, Clatot F, Goncalves A, Chabaud S, Cottu P Long-Term Results with Everolimus in Advanced Hormone Receptor Positive Breast Cancer in a Multicenter National Real-World Observational Study. Cancers (Basel). 2023;15(4):1191. doi:10.3390/cancers15041191

Bardol T, Eslami-S Z, Masmoudi D, Alexandre M, Duboys de Labarre M, D'Hondt V, Guiu S, Kurma K, Cayrefourcq L, Jacot W, Alix-Panabières C First evidence of AXL expression on circulating tumor cells in metastatic breast cancer patients: A proof-of-concept study. Cancer Med. 2023-12-22. doi:10.1002/cam4.6843

Rabia E, Garambois V, Dhommée C, Larbouret C, Lajoie L, Buscail Y, Jimenez-Dominguez G, Choblet-Thery S, Liaudet-Coopman E, Cerutti M, Jarlier M, Ravel P, Gros L, Pirot N, Thibault G, Zhukovsky E, Gérard P-E, Pèlegrin A, Colinge J, Chardès T Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer. Front Immunol. 2023;14. doi:10.3389/fimmu.2023.1168444

David T, Mallavialle A, Faget J, Alcaraz L, Lapierre M, du Roure P, Laurent-Matha V, Mansouri H, Jarlier M, Martineau P, Roger P, Guiu S, Chardès T, Liaudet-Coopman E Anti-cathepsin D immunotherapy triggers both innate and adaptive anti-tumour immunity in breast cancer. Br J Pharmacol. 2023-11-29. doi:10.1111/bph.16291

Eberlé M-C, Fersing C, Guillemard S, Ilonca D, Guiu S, Deshayes E Unusual Focal Lung Uptake without CT Abnormality on a Bone Scan: What Might It Mean?. Diagnostics (Basel). 2022;12(4):934. doi:10.3390/diagnostics12040934

Alcaraz L, Mallavialle A, Mollevi C, Boissière-Michot F, Mansouri H, Simony-Lafontaine J, Laurent-Matha V, Chardès T, Jacot W, Turtoi A, Roger P, Guiu S, Liaudet-Coopman E SPARC in cancer-associated fibroblasts is an independent poor prognostic factor in non-metastatic triple-negative breast cancer and exhibits pro-tumor activity. Int J Cancer. 2022-11-08. doi:10.1002/ijc.34345

Rovera C, Berestjuk I, Lecacheur M, Tavernier C, Diazzi S, Pisano S, Irondelle M, Mallavialle A, Albrengues J, Gaggioli C, Girard C, Passeron T, Deckert M, Tartare-Deckert S Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells. Cancer Res. 2022;82(9):1774-1788. doi:10.1158/0008-5472.CAN-21-0501

Mallet A, Levy C, Pistilli B, Brain E, Pasquier D, Debled M, Thery J, Desmoulins I, De La Motte Rouge T, Faure C, Ferrero J, Eymard J, Mouret-Reynier M, Patsouris A, Cottu P, Dalenc F, Petit T, Payen O, Uwer L, Guiu S, Sébastien Frenel J Real-world evidence of the management and prognosis of young women (?40?years) with de novo metastatic breast cancer. Ther Adv Med Oncol. 2022;14. doi:10.1177/17588359211070362

Leenhardt F, Gauthier L, Alexandre M, Guiu S, Firmin N, Viala M, Lossaint G, Gautier C, Mollevi C, Gracia M, Mbatchi L, Evrard A, Jacot W Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug-Drug Interactions Are the Usual Suspects. Pharmaceutics. 2022;14(4):841. doi:10.3390/pharmaceutics14040841

Dalenc F, De La Motte Rouge T, Pistilli B, Brain E, Pasquier D, Debled M, Desmoulins I, Levy C, Uwer L, Ferrero J-M, Eymard J-C, Mouret-Reynier M-A, Patsouris A, Frenel J-S, Petit T, Bachelot T, Guiu S Impact of lobular versus ductal histology on overall survival in metastatic breast cancer: a French retrospective multicentre cohort study. Eur J Cancer. 2022;164. doi:10.1016/j.ejca.2021.12.031

Fabbro M, Jacot W, Jarlier M, Guiu S, D'Hondt V, Champoiral P, Janiszewski C, Nicklès I Hypnosis on patients treated with adjuvant chemotherapy for breast cancer: A feasibility study. Cancer Rep (Hoboken). 2022-10-27. doi:10.1002/cnr2.1732

Baudry A-S, Vanlemmens L, Congard A, Untas A, Segura-Djezzar C, Lefeuvre-Plesse C, Coussy F, Guiu S, Frenel J-S, Sauterey B, Yakimova S, Christophe V Emotional processes in partners' quality of life at various stages of breast cancer pathway: a longitudinal study. Qual Life Res. 2022-11-24. doi:10.1007/s11136-022-03298-6

Vasseur A, Carton M, Augereau P, Uwer L, Mouret-Reynier M-A, Levy C, Eymard J-C, Ferrero J-M, Leheurteur M, Goncalves A, Robert M, De La Motte Rouge T, Bachelot T, Petit T, Debled M, Grinda T, Desmoulins I, Vanlemmens L, Nicolaï V, Simon G, Cabel L Efficacy of taxanes rechallenge in first-line treatment of early metastatic relapse of patients with HER2-negative breast cancer previously treated with a (neo)adjuvant taxanes regimen: A multicentre retrospective observational study. Breast. 2022;65. doi:10.1016/j.breast.2022.07.014

Bergeret B, Masset F, Bekoy Y, Roger P, Habib F, Ovtchinnikoff B, Meunier L, Stoebner P Diagnostic Accuracy of Digital Staining ex vivo Confocal Microscopy for Diagnosing and Subtyping Basal Cell Carcinoma in Fresh Pretherapeutic Punch Biopsies: A Monocentric Prospective Study. Dermatology. 2022-05-05. doi:10.1159/000524349

Boissière-Michot F, Chateau M-C, Guiu S, Jacot W Correlation of the TIGIT-PVR immune checkpoint axis with clinicopathological features in triple-negative breast cancer. Front Immunol. 2022;13. doi:10.3389/fimmu.2022.1058424

Carausu M, Carton M, Petit T, Guiu S, Augereau P, Ferrero J, Levy C, Ung M, Desmoulins I, Debled M, Bachelot T, Pistilli B, Frenel J-S, Mailliez A, Chevrot M, Cabel L Association of Endocrine Therapy for HR+/ERBB2+ Metastatic Breast Cancer With Survival Outcomes. JAMA Netw Open. 2022;5(12):e2247154. doi:10.1001/jamanetworkopen.2022.47154

Baudry A-S, Yakimova S, Congard A, Untas A, Guiu S, Lefeuvre-Plesse C, Loustalot C, Guillemet C, Segura-Djezzar C, Savoye A-M, Coussy F, Frenel J-S, Vanlemmens L, Christophe V Adjustment of young women with breast cancer after chemotherapy: A mediation model of emotional competence via emotional distress. Psychooncology. 2022-01-05. doi:10.1002/pon.5876

Franchet C, Djerroudi L, Maran-Gonzalez A, Abramovici O, Antoine M, Berghian A, Blanc-Fournier C, Brabencova E, Charafe-Jauffret E, Chenard M-P, Dauplat M-M, Delrée P, Fleury C, Ghnassia J-P, Haudebourg J, Leroux A, Mathieu M-C, Michenet P, Penault-Llorca F, Poulet B, Robin Y, Roger P, Russ E, Tixier L, Treilleux I, Valent A, Verriele V, Vincent-Salomon A, Arnould L, Lacroix-Triki M [2021 update of the GEFPICS' recommendations for HER2 status assessment in invasive breast cancer in France]. Ann Pathol. 2021-08-12. doi:10.1016/j.annpat.2021.07.014

Culié D, Viotti J, Modesto A, Schiappa R, Chamorey E, Dassonville O, Poissonnet G, Guelfucci B, Bizeau A, Vergez S, Dupret-Bories A, Garrel R, Fakhry N, Santini L, Lallemant B, Chambon G, Sudaka A, Peyrade F, Saada-Bouzid E, Benezery K, Jourdan-Soulier F, Chapel F, Ramay A, Roger P, Galissier T, Coste V, Ben Lakdar A, Guerlain J, Temam S, Mirghani H, Gorphe P, Bozec A Upfront surgery or definitive radiotherapy for patients with p16-negative oropharyngeal squamous cell carcinoma. A GETTEC multicentric study. Eur J Surg Oncol. 2021;47(2):367-374. doi:10.1016/j.ejso.2020.07.034

Rittore C, Méchin D, Sanchez E, Marinèche L, Ea V, Soler S, Vereecke M, Mallavialle A, Richard E, Duroux-Richard I, Apparailly F, Touitou I, Grandemange S TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNF?/TNFR1 signalling regulation in the pathophysiology of TRAPS. Sci Rep. 2021;11(1):4172. doi:10.1038/s41598-021-83539-9

Berestjuk I, Lecacheur M, Carminati A, Diazzi S, Rovera C, Popovic A, Mallavialle A, Larbret F, Pisano S, Audebert S, Passeron T, Gaggioli C, Girard C, Deckert M, Tartare-Deckert S Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma. EMBO Mol Med. 2021-12-27. doi:10.15252/emmm.201911814

Milliet F, Bozec A, Schiappa R, Viotti J, Modesto A, Dassonville O, Poissonnet G, Guelfucci B, Bizeau A, Vergez S, Dupret-Bories A, Garrel R, Fakhry N, Santini L, Lallemant B, Chambon G, Sudaka A, Peyrade F, Saada-Bouzid E, Benezery K, Jourdan-Soulier F, Chapel F, Sophie Ramay A, Roger P, Galissier T, Coste V, Ben Lakdar A, Guerlain J, Temam S, Mirghani H, Gorphe P, Chamorey E, Culié D Synchronous primary neoplasia in patients with oropharyngeal cancer: Impact of tumor HPV status. A GETTEC multicentric study. Oral Oncol. 2021;112. doi:10.1016/j.oraloncology.2020.105041



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