Our team aims to unravel phosphorylation-based signaling pathways involved in the regulation of tumor progression and treatment resistance with a theranostic purpose.
Aptecar L, Puech C, Lopez-Crapez E, Peter M, Coopman P, D'Hondt V, Freiss GPTPN13 Participates in the Regulation of Epithelial-Mesenchymal Transition and Platinum Sensitivity in High-Grade Serous Ovarian Carcinoma Cells. Int J Mol Sci. 2023;24(20):15413. doi:10.3390/ijms242015413
Coopman PProtein Phosphorylation in Cancer: Unraveling the Signaling Pathways. Biomolecules. 2022;12(8):1036. doi:10.3390/biom12081036
Buffard M, Naldi A, Freiss G, Deckert M, Radulescu O, Coopman P, Larive RComparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions. Biomolecules. 2021;11(2). doi:10.3390/biom11020308
Béganton B, Coyaud E, Laurent E, Mangé A, Jacquemetton J, Le Romancer M, Raught B, Solassol JProximal Protein Interaction Landscape of RAS Paralogs. Cancers. 2020;12(11):3326. doi:10.3390/cancers12113326