Research
Drug resistance and new cancer treatments : C. Gongora

RESEARCH TOPICS

Our laboratory is interested in the mechanisms of drug resistance in digestive and urological cancers, and the means to overcome them by activating the antitumoral immune system.

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MAIN PUBLICATIONS

Combes E, Andrade A, Tosi D, Michaud H-A, Coquel F, Desigaud D, Jarlier M, Coquelle A, Pasero P, Bonnefoy N, Martineau P, Del Rio M, Beijersbergen R, Vezzio-Vie N Inhibition of Ataxia-Telangiectasia Mutated and RAD3-related (ATR) overcomes oxaliplatin resistance and promotes anti-tumor immunity in colorectal cancer. Cancer Res.. Apr 15, 2019. doi:10.1158/0008-5472.CAN-18-2807

Cherradi S, Martineau P, Gongora C, Del Rio M Claudin gene expression profiles and clinical value in colorectal tumors classified according to their molecular subtype. Cancer Manag Res. 2019;11. doi:10.2147/CMAR.S188192

Corvaglia V, Carbajo D, Prabhakaran P, Ziach K, Mandal P, Santos V, Legeay C, Vogel R, Parissi V, Pourquier P, Huc I Carboxylate-functionalized foldamer inhibitors of HIV-1 integrase and Topoisomerase 1: artificial analogues of DNA mimic proteins. Nucleic Acids Res.. May 10, 2019. doi:10.1093/nar/gkz352

Ziach K, Chollet C, Parissi V, Prabhakaran P, Marchivie M, Corvaglia V, Bose P, Laxmi-Reddy K, Godde F, Schmitter J-M, Chaignepain S, Pourquier P, Huc I Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA. Nat Chem. 2018;10(5):511-518. doi:10.1038/s41557-018-0018-7

Cherradi S, Ayrolles-Torro A, Vezzo-Vié N, Gueguinou N, Denis V, Combes E, Busson M, Canterel-Thouennon L, Mollevi C, Pugnière M, Bibeau F, Ychou M, Martineau P, Gongora C, Del Rio M Antibody targeting of claudin-1 as a potential colorectal cancer therapy. J. Exp. Clin. Cancer Res.. 2017;36(1):89. doi:10.1186/s13046-017-0558-5


Team

Team Leader  : Céline Gongora
 

Institut de Recherche en
Cancérologie de Montpellier
Campus Val d’Aurelle
34298 Montpellier cedex 5

Tél. : 33 (0)4 11 28 31 09
celine.gongora@inserm.fr

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partners / funding

                              


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés