Research
Cancer bioinformatics and systems biology : J. Colinge

activities

We are interested in the discovery of informative structures in omics datasets by means of systems biology and machine learning approaches. We apply our methods to cancer and other diseases.

                                 More                              

     

main Publications

Lehmann S, Vialaret J, Gabelle A, Bauchet L, Villemin J-P, Hirtz C, Colinge J Enabling population protein dynamics through Bayesian modeling. Bioinformatics. 2024;40(8):btae484. doi:10.1093/bioinformatics/btae484

Honda C, Kurozumi S, Fujii T, Pourquier D, Khellaf L, Horiguchi J, Oyama T, Shirabe K, Colinge J, Yokobori T, Turtoi A Cancer-associated fibroblast spatial heterogeneity and EMILIN1 expression in the tumor microenvironment modulate TGF-? activity and CD8+ T-cell infiltration in breast cancer. Theranostics. 2024;14(5):1873-1885. doi:10.7150/thno.90627

Villemin J-P, Bassaganyas L, Pourquier D, Boissière F, Cabello-Aguilar S, Crapez E, Tanos R, Cornillot E, Turtoi A, Colinge J Inferring ligand-receptor cellular networks from bulk and spatial transcriptomic datasets with BulkSignalR. Nucleic Acids Res. 2023-05-05. doi:10.1093/nar/gkad352

Giguelay A, Turtoi E, Khelaf L, Tosato G, Dadi I, Chastel T, Poul M-A, Pratlong M, Nicolescu S, Severac D, Adenis A, Sgarbura O, Carrère S, Rouanet P, Ychou M, Pourquier D, Colombo P-E, Turtoi A, Colinge J The landscape of cancer-associated fibroblasts in colorectal cancer liver metastases. Theranostics. 2022;12(17):7624-7639. doi:10.7150/thno.72853

Cabello-Aguilar S, Alame M, Kon-Sun-Tack F, Fau C, Lacroix M, Colinge J SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics. Nucleic Acids Res.. Mar 20, 2020. doi:10.1093/nar/gkaa183


Team

Team Leader  : Jacques Colinge
 

Institut de Recherche en
Cancérologie de Montpellier
Campus Val d’Aurelle
34298 Montpellier cedex 5


 

Tél. : 33 (0)4 11 28 31 18
jacques.colinge@inserm.fr

 

partners / funding


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés