Recherche
Régulation Epigénétique et Cancer : E. Julien

Publications

Rossitto M, Déjardin S, Rands C, Le Gras S, Migale R, Rafiee M-R, Neirijnck Y, Pruvost A, Nguyen A, Bossis G, Cammas F, Le Gallic L, Wilhelm D, Lovell-Badge R, Boizet-Bonhoure B, Nef S, Poulat F TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway. Nat Commun. 2022;13(1):4412. doi:10.1038/s41467-022-32061-1

Fesquet D, Grimaud C, Viganò C, Boulon S, Coux O, Bonne-Andrea C, Baldin V The 20S proteasome activator PA28? controls the compaction of chromatin. 2021;134(3):jcs257717. doi:10.1242/jcs.257717

Herviou L, Ovejero S, Izard F, Karmous-Gadacha O, Gourzones C, Bellanger C, De Smedt E, Ma A, Vincent L, Cartron G, Jin J, De Bruyne E, Grimaud C, Julien E, Moreaux J Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma. Clin Epigenet. 2021;13(1):174. doi:10.1186/s13148-021-01160-z

Mancini M, Papon L, Mangé A, Cammas F, Fabbrizio E HP1s modulate the S-Adenosyl Methionine synthesis pathway in liver cancer cells. 2020;477(5):1033-1047. doi:10.1042/BCJ20190621

Jonik-Nowak B, Menneteau T, Fesquet D, Baldin V, Bonne-Andrea C, Fabre B, Boisguerin P, de Rossi S, Henriquet C, Pugnière M, Ducoux-Petit M, Burlet-Schiltz O, Lamond A, Fort P, Boulon S, Bousquet M-P, Coux O PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28?. Proc. Natl. Acad. Sci. U.S.A.. 2018;115(28):E6477-E6486. doi:10.1073/pnas.1722299115

Shoaib M, Walter D, Gillespie P, Izard F, Fahrenkrog B, Lleres D, Lerdrup M, Johansen J, Hansen K, Julien E, Blow J, Sørensen C Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing. Nat Commun. 2018;9(1):3704. doi:10.1038/s41467-018-06066-8

Mestre-Francés N, Serratrice N, Gennetier A, Devau G, Cobo S, Trouche S, Fontès P, Zussy C, De Deurwaerdere P, Salinas S, Mennechet F, Dusonchet J, Schneider B, Saggio I, Kalatzis V, Luquin-Piudo M, Verdier J-M, Kremer E Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate. JCI Insight. 2018;3(14). doi:10.1172/jci.insight.98202

Zouaz A, Fernando C, Perez Y, Sardet C, Julien E, Grimaud C Cell-cycle regulation of non-enzymatic functions of the Drosophila methyltransferase PR-Set7. Nucleic Acids Res.. 2018;46(6):2834-2849. doi:10.1093/nar/gky034

Zitouni S, Papin C, Choquet A, Roche D, Baldin V, Coux O, Bonne-Andrea C The stability of Fbw7? in M-phase requires its phosphorylation by PKC. PLoS ONE. 2017;12(8):e0183500. doi:10.1371/journal.pone.0183500

Rahmoun M, Lavery R, Laurent-Chaballier S, Bellora N, Philip G, Rossitto M, Symon A, Pailhoux E, Cammas F, Chung J, Bagheri-Fam S, Murphy M, Bardwell V, Zarkower D, Boizet-Bonhoure B, Clair P, Harley V, Poulat F In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures. Nucleic Acids Res.. 2017;45(12):7191-7211. doi:10.1093/nar/gkx328

Barjon C, Michaud H-A, Fages A, Dejou C, Zampieri A, They L, Gennetier A, Sanchez F, Gros L, Eliaou J-F, Bonnefoy N, Lafont V IL-21 promotes the development of a CD73-positive V?9V?2 T cell regulatory population. Oncoimmunology. 2017;7(1):e1379642. doi:10.1080/2162402X.2017.1379642

Brustel J, Kirstein N, Izard F, Grimaud C, Prorok P, Cayrou C, Schotta G, Abdelsamie A, Déjardin J, Méchali M, Baldacci G, Sardet C, Cadoret J-C, Schepers A, Julien E Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication. EMBO J.. 2017;36(18):2726-2741. doi:10.15252/embj.201796541

Williams D, Izard F, Arnould S, Dalisay D, Tantapakul C, Maneerat W, Matainaho T, Julien E, Andersen R Structures of Nahuoic Acids B-E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A. J. Org. Chem.. 2016;81(4):1324-1332. doi:10.1021/acs.joc.5b02569

Fasching L, Kapopoulou A, Sachdeva R, Petri R, Jönsson M, Männe C, Turelli P, Jern P, Cammas F, Trono D, Jakobsson J TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells. 2015;10(1):20-28. doi:10.1016/j.celrep.2014.12.004

Rodier G, Kirsh O, Baraibar M, Houlès T, Lacroix M, Delpech H, Hatchi E, Arnould S, Severac D, Dubois E, Caramel J, Julien E, Friguet B, Le Cam L, Sardet C The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions. Cell Rep. 2015;11(2):220-233. doi:10.1016/j.celrep.2015.03.024

Harouz H, Rachez C, Meijer B, Marteyn B, Donnadieu F, Cammas F, Muchardt C, Sansonetti P, Arbibe L Shigella flexneri targets the HP1 subcode through the phosphothreonine lyase OspF. 2014;33(22):2606-2622. doi:10.15252/embj.201489244

Thomas Y, Peter M, Mechali F, Blanchard J-M, Coux O, Baldin V Kizuna is a novel mitotic substrate for CDC25B phosphatase. Cell Cycle. 2014;13(24):3867-3877. doi:10.4161/15384101.2014.972882

Loukil A, Zonca M, Rebouissou C, Baldin V, Coux O, Biard-Piechaczyk M, Blanchard J-M, Peter M High-resolution live-cell imaging reveals novel cyclin A2 degradation foci involving autophagy. J. Cell. Sci.. 2014;127(Pt 10):2145-2150. doi:10.1242/jcs.139188

Serratrice N, Cubizolle A, Ibanes S, Mestre-Francés N, Bayo-Puxan N, Creyssels S, Bernex F, Verdier J-M, Haskins M, Couderc G, Malecaze F, Kalatzis V, Kremer E Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector. J Control Release. 2014;181. doi:10.1016/j.jconrel.2014.02.022

Cubizolle A, Serratrice N, Skander N, Colle M-A, Ibanes S, Bayo-Puxan N, Mazouni K, Mennechet F, Joussemet B, Cherel Y, Lajat Y, Vite C, Bernex F, Kalatzis V, Haskins M, Kremer E Corrective GUSB transfer to the canine mucopolysaccharidosis VII brain. Mol. Ther.. 2014;22(4):762-773. doi:10.1038/mt.2013.283

Piersanti S, Astrologo L, Licursi V, Costa R, Roncaglia E, Ibanes S, Chillon M, Negri R, Tagliafico E, Kremer E, Saggio I Differentiated neuroprogenitor cells incubated with human or canine adenovirus, or lentiviral vectors have distinct transcriptome profiles. PLoS ONE. 2013;8(7):e69808. doi:10.1371/journal.pone.0069808

Brustel J, Tardat M, Kirsh O, Grimaud C, Julien E Coupling mitosis to DNA replication: the emerging role of the histone H4-lysine 20 methyltransferase PR-Set7. Trends Cell Biol.. 2011;21(8):452-460. doi:10.1016/j.tcb.2011.04.006

Tardat M, Brustel J, Kirsh O, Lefevbre C, Callanan M, Sardet C, Julien E The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells. Nat. Cell Biol.. 2010;12(11):1086-1093. doi:10.1038/ncb2113

Delorme R, Moreno-De-Luca D, Gennetier A, Maier W, Chaste P, Mössner R, Grabe H, Ruhrmann S, Falkai P, Mouren M-C, Leboyer M, Wagner M, Betancur C Search for copy number variants in chromosomes 15q11-q13 and 22q11.2 in obsessive compulsive disorder. BMC Med. Genet.. 2010;11. doi:10.1186/1471-2350-11-100

Grimaud C, Becker P Form and function of dosage-compensated chromosomes--a chicken-and-egg relationship. Bioessays. 2010;32(8):709-717. doi:10.1002/bies.201000029



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